Menopause & perimenopause care
Feel more like
yourself again.
Hormone therapy for menopause symptoms, prescribed online by a licensed provider and personalized to how you feel.
Have you tried hormone therapy before?
One cream, two hormones
Hormone care, matched to your symptoms.
Many menopause symptoms come from falling estrogen and progesterone levels. Your provider reviews what you are experiencing and, if it is right for you, prescribes a cream that combines both.
Compounded · Rx only
Estradiol / Progesterone Cream
Estradiol
A bioidentical estrogen that can help with hot flashes, night sweats, sleep and vaginal dryness.
Progesterone
Helps protect the uterine lining for women taking estrogen who still have a uterus.
- Applied to the skin, no pills to swallow
- Strengths set by your provider
- Adjusted if your symptoms change
$149/monthIncludes your provider visit, medication and shipping.
See if it's right for meCompounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness or quality. Prescription required. Not everyone will qualify.
Start with how you feel
What's bothering you most?
Perimenopause and menopause can show up in dozens of ways. Pick one to start your intake — you can tell your provider about all of them.
What to expect
Your first three months.
- Day 1
Tell us how you feel
Answer a short, private intake about your symptoms and health history. A licensed provider reviews it, usually within 24 hours.
- Week 1
Your cream arrives
If your provider prescribes treatment, your cream ships from a licensed U.S. pharmacy in discreet packaging, with instructions for use.
- Weeks 2–6
Early changes
Some women begin to notice changes in sleep, hot flashes and comfort over the first several weeks. Everyone responds differently.
- Weeks 8–12
Fine-tune your plan
Check in with your provider about how you feel. Your dose can be adjusted so your plan keeps fitting you.
Individual results vary. Timelines are typical, not guaranteed.
Why OneClick Rx
Care that keeps fitting you.
Your hormones change. Your plan should be able to change with them.
Dosed for you
Your provider chooses your estradiol and progesterone strengths based on your symptoms and history.
Adjusted as needed
Not feeling right? Your provider can change your dose at any point in your plan.
Message your care team
Questions about side effects, timing or refills? Message your care team from your account.
Refills on schedule
Your cream ships to your door with tracking, and refills arrive before you run out.
Licensed providers
Every intake is reviewed by a provider licensed in your state.
100% online
No waiting rooms or office visits. Start from your phone or computer.
Personalization matters
Not a one-size-fits-all product.
Over-the-counter menopause products come in one strength for everyone. Your plan is prescribed for you and can be adjusted over time.
Simple pricing
Everything you need, one monthly price.
No membership fees and no surprise charges. You are only charged if your provider prescribes treatment.
Estradiol / Progesterone Cream
Starting at$149/month
- Online visit with a state-licensed provider
- Compounded estradiol / progesterone cream, if prescribed
- Dose adjustments when needed
- Messaging with your care team
- Free, discreet shipping with tracking
No membership fees · Cancel anytime
3 simple steps
Reviewed in about a day. Shipped after approval.
Complete your intake
Tell us about your symptoms, cycle and health history. It takes about 10 minutes.
Get your provider's review
A licensed provider reviews your answers and, if treatment is right for you, prescribes your cream.
Get ongoing support
Message your care team with questions, dose changes and refills whenever you need.
Important safety information
Hormone therapy
Estrogen therapy has boxed warnings for increased risk of endometrial cancer, stroke, blood clots, heart attack, breast cancer and probable dementia in some women.
Progesterone can cause drowsiness, dizziness, headache, breast tenderness and mood changes. When combined with estrogen, it carries the same boxed warnings for blood clots, stroke, heart attack, breast cancer and probable dementia.
This is a summary only and does not include all possible risks. Talk with your provider and pharmacist. Report side effects to the FDA at 1-800-FDA-1088.
FAQ
You have questions. We have answers.
More answers on our FAQ page, or email support@oneclickrx.com.
What is in the cream?
It combines estradiol, a bioidentical form of estrogen, with progesterone in one topical cream. It is compounded by a licensed U.S. pharmacy for each patient, in the strengths your provider prescribes.
Why does it include progesterone?
For women who still have a uterus, taking estrogen alone raises the risk of endometrial cancer. Progesterone helps protect the lining of the uterus. Your provider will explain what is right for you.
How do I use it?
Your provider and pharmacy label will tell you how much to apply, where and when. Do not change your dose without talking to your provider.
How fast will I feel a difference?
It varies. Some women notice changes within a few weeks, while for others it takes longer or needs a dose adjustment. Your provider will check in with you along the way.
Am I a candidate?
Hormone therapy is not right for everyone. It is generally not prescribed if you have had breast or endometrial cancer, blood clots, a stroke or heart attack, liver disease or unexplained vaginal bleeding, or if you are pregnant. Your provider will review your full history.
How much does it cost?
Plans start at $149/month and include your provider visit, medication and shipping. You are only charged if your provider prescribes treatment.
Which states do you serve?
We currently serve patients in 49 states (not California).
Do I need lab work?
Often, yes. Your provider may order labs to confirm a diagnosis and to monitor you during treatment.
Are compounded hormone creams FDA-approved?
No. Compounded medications are not FDA-approved and the FDA does not review them for safety, effectiveness or quality. Your provider will discuss FDA-approved options with you.
Ready for relief that fits you?
Complete a short, private intake and a licensed provider will review whether hormone therapy is right for you.